VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Domestic guinea pig

Scientific Name: Cavia porcellus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Hystricomorpha-> Caviidae-> Cavia

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Human mastadenovirus B

Family: Adenoviridae

Receptor: CD86

Receptor CD86 information

Summary: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0058 2021.04 iDrop PBMC Normal 11140 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of CD86 in human tissues   [NCBI]

Expression: Broad expression in appendix (RPKM 16.6), lymph node (RPKM 11.0) and 16 other tissues?

Protein expression of CD86 in human tissues   [Proteinatlas]